GHSR antibody (C-Term)

Catalog No. ABIN655816

Product Details anti-GHSR Antibody

Target: GHSR (Growth Hormone Secretagogue Receptor (GHSR))

Binding Specificity: AA 326-357, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GHSR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Pig, Rb

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GHSR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-357 amino acids from the C-terminal region of human GHSR.

Clone: RB18124

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for GHSR

Target: GHSR (Growth Hormone Secretagogue Receptor (GHSR))

Alternative Name: GHSR (GHSR Products)

Synonyms: GHSR antibody, C530020I22Rik antibody, growth hormone secretagogue receptor antibody, growth hormone secretagogue receptor,putative antibody, GHSR antibody, Smp_164730 antibody, Ghsr antibody

Background: This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein, this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin, however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.

Molecular Weight: 41329

Gene ID: 2693

NCBI Accession: NP_004113, NP_940799

UniProt: Q92847

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Feeding Behaviour