TGFB1 antibody (AA 30-50)
-
- Target See all TGFB1 Antibodies
- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
-
Binding Specificity
- AA 30-50
-
Reactivity
- Human, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This TGFB1 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Predicted Reactivity
- B, Hs, Pig, Rat
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This TGFB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-50 amino acids of human TGFB1.
- Clone
- RB20803
- Isotype
- IgG
- Top Product
- Discover our top product TGFB1 Primary Antibody
-
-
- Application Notes
- WB: 1:2000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
-
-
CTGF siRNA ameliorates tubular cell apoptosis and tubulointerstitial fibrosis in obstructed mouse kidneys in a Sirt1-independent manner." in: Drug design, development and therapy, Vol. 9, pp. 4155-71, (2015) (PubMed).
: "
-
CTGF siRNA ameliorates tubular cell apoptosis and tubulointerstitial fibrosis in obstructed mouse kidneys in a Sirt1-independent manner." in: Drug design, development and therapy, Vol. 9, pp. 4155-71, (2015) (PubMed).
-
- Target
- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
- Alternative Name
- TGFB1 (TGFB1 Products)
- Background
- TGFB1 is a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
- Molecular Weight
- 44341
- Gene ID
- 7040
- NCBI Accession
- NP_000651
- UniProt
- P01137
- Pathways
- EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints
-