Intercellular Adhesion Molecule 3 (ICAM3) (AA 282-310), (Center) antibody

Details for Product No. ABIN657631
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Antigen
Epitope
AA 282-310, Center
(16), (10), (7), (7), (7), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(166)
Host
Rabbit
(101), (63), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(21), (14), (12), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(97), (54), (54), (27), (23), (16), (14), (10), (10), (8), (5), (5), (2), (1), (1), (1), (1)
Pubmed 2 references available
Quantity 400 μL
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Catalog No. ABIN657631
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Immunogen This ICAM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-310 AA from the Central region of human ICAM3.
Clone RB33648
Isotype Ig
Specificity This ICAM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-310 amino acids from the Central region of human ICAM3.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ICAM3
Background The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule.
Synonyms: Intercellular adhesion molecule 3,ICAM3,
Molecular Weight 59541 DA
Gene ID 3385
NCBI Accession NP_002153
UniProt P32942
Research Area Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.37 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment ICAM3 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Intercellular Adhesion Molecule 3 (ICAM3) (AA 282-310), (Center) antibody ICAM3 Antibody (Center) (ABIN657631) western blot analysis in ZR-75-1 cell line lysates (35 µg/lane). This demonstrates the ICAM3 antibody detected the ICAM3 protein (arrow).
Background publications Mosbruger, Duggal, Goedert et al.: "Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus." in: The Journal of infectious diseases, Vol. 201, Issue 9, pp. 1371-80, 2010 (PubMed).

Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).

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