BST2 Protein (AA 50-161) (His tag)
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- Target See all BST2 Proteins
- BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 50-161
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BST2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- BST2, 50-161aa, Human, His tag, E.coli
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product BST2 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
- Storage
- 4 °C
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- Target
- BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
- Alternative Name
- BST2 (BST2 Products)
- Synonyms
- BST2 Protein, CD317 Protein, TETHERIN Protein, 2310015I10Rik Protein, Bst-2 Protein, C87040 Protein, DAMP-1 Protein, GREG Protein, Damp1 Protein, bone marrow stromal cell antigen 2 Protein, bone marrow stromal antigen 2 Protein, BST2 Protein, LOC618737 Protein, Bst2 Protein
- Background
- BST2, also known as bone marrow stromal antigen 2, is involved in the growth and development of B-cells. BST2 is a human cellular protein which inhibits retrovirus infection by preventing the diffusion of virus particles after budding from infected cells. Initially discovered as an inhibitor to HIV-1 infection in the absence of Vpu, tetherin has also been shown to inhibit the release of other viruses such as the Lassa and Marburg virions. Also, this protein may play a role in B-cell activation in rheumatoid arthritis. Recombinant human BST2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Bone marrow stromal antigen 2, HM1.24 antigen, Tetherin, CD317. NCBI no.: NP_004326
- Molecular Weight
- 14.8 kDa (133aa), confirmed by MALDI-TOF
- Pathways
- Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
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