CD40 Ligand antibody (CD40LG) (AA 47-80)

Details for Product anti-CD40LG Antibody No. ABIN674439, Supplier: Log in to see
Antigen
  • CD154
  • cd40l
  • CD40L
  • HIGM1
  • IGM
  • IMD3
  • T-BAM
  • TNFSF5
  • TRAP
  • gp39
  • hCD40L
  • CD40-L
  • Cd40l
  • Ly-62
  • Ly62
  • Tnfsf5
  • CD40 ligand
  • TNF superfamily member 5
  • CD40LG
  • cd40l
  • Cd40lg
  • LOC100358388
  • CD154
Alternatives
anti-Human CD40 Ligand antibody for Functional Studies
Epitope
AA 47-80
26
24
21
15
15
15
9
9
9
7
6
6
5
4
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
493
251
54
20
20
10
8
8
6
5
4
3
3
3
3
2
2
1
Host
Rabbit
303
174
111
51
45
28
2
1
Clonality
Polyclonal
Conjugate
This CD40 Ligand antibody is un-conjugated
75
61
46
17
17
15
15
11
9
9
9
9
9
9
9
8
8
7
7
7
7
6
4
4
4
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
434
298
173
109
68
63
51
43
34
20
17
17
13
12
9
9
6
5
4
4
2
2
2
1
1
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen KLH conjugated synthetic peptide derived from human CD40L/CD154
Isotype IgG
Purification Purified by Protein A.
Alternative Name Cd40l (CD40LG Antibody Abstract)
Background

Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD4L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.

Subcellular location: Extracellular

Synonyms: IGM, IMD3, TRAP, gp39, CD154, CD4L, HIGM1, T-BAM, TNFSF5, hCD4L, CD4 ligand, CD4-L, T-cell antigen Gp39, TNF-related activation protein, Tumor necrosis factor ligand superfamily member 5, CD4LG

Gene ID 959
UniProt P29965
Pathways NF-kappaB Signaling, Production of Molecular Mediator of Immune Response
Application Notes FCM 1:20-100
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months
Supplier Images
Flow Cytometry (FACS) image for anti-CD40 Ligand (CD40LG) (AA 47-80) antibody (ABIN674439) U937 cells probed with Rabbit Anti-CD40L Polyclonal Antibody (ABIN674439) at 1:100 fo...
Flow Cytometry (FACS) image for anti-CD40 Ligand (CD40LG) (AA 47-80) antibody (ABIN674439) Rat spleen cells probed with Rabbit Anti-CD40L Polyclonal Antibody Alexa Fluor 488 C...
Product cited in: Zhang, Song, Shu, Li, Wu, Wang, Chen, Chang, Wu, Zhang, Wei: "BAFF upregulates CD28/B7 and CD40/CD154 expression and promotes mouse T and B cell interaction in vitro via BAFF receptor." in: Acta pharmacologica Sinica, Vol. 37, Issue 8, pp. 1101-9, 2016 (PubMed).