CITED1 antibody (AA 121-193)
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- Target See all CITED1 Antibodies
- CITED1 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 1 (CITED1))
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Binding Specificity
- AA 121-193
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CITED1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CITED1
- Isotype
- IgG
- Top Product
- Discover our top product CITED1 Primary Antibody
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- CITED1 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 1 (CITED1))
- Alternative Name
- CITED1 (CITED1 Products)
- Synonyms
- cited1 antibody, fi05d05 antibody, CITED1 antibody, MSG1 antibody, AI316840 antibody, AU019144 antibody, Msg1 antibody, Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 antibody, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 antibody, similar to Cbp/p300-interacting transactivator 1 (Melanocyte-specific protein 1) antibody, Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 antibody, cited1 antibody, CITED1 antibody, Cited1 antibody
- Background
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Synonyms: MSG1, Cbp/p300-interacting transactivator 1, Melanocyte-specific protein 1, CITED1
Background: Transcriptional coactivator of the p300/CBP-mediated trancription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling, stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner.
- Gene ID
- 4435
- UniProt
- Q99966
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