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MICA antibody (AA 120-170)

MICA Reactivity: Human WB, IHC (p), IF (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN728788
  • Target See all MICA Antibodies
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    Binding Specificity
    • 8
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 120-170
    Reactivity
    • 69
    • 18
    • 14
    • 11
    • 7
    • 5
    • 2
    • 1
    Human
    Host
    • 36
    • 33
    Rabbit
    Clonality
    • 36
    • 34
    Polyclonal
    Conjugate
    • 44
    • 8
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MICA antibody is un-conjugated
    Application
    • 44
    • 37
    • 33
    • 19
    • 17
    • 12
    • 9
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MICA
    Isotype
    IgG
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  • Application Notes
    WB 1:100-1000
    IHC-P 1:100-500
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Chen, Zhidan, Xia, Zhaoxia, Qing, Qiang, Haipeng, Hengxiao: "Scorpion venom activates natural killer cells in hepatocellular carcinoma via the NKG2D-MICA pathway." in: International immunopharmacology, Vol. 35, pp. 307-14, (2016) (PubMed).

  • Target
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    Alternative Name
    MICA (MICA Products)
    Synonyms
    MIC-A antibody, PERB11.1 antibody, MHC class I polypeptide-related sequence A antibody, MICA antibody
    Background

    Synonyms: MIC-A, PERB11.1, MHC class I polypeptide-related sequence A, MICA

    Background: Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.

    Gene ID
    100507436
    UniProt
    Q29983
    Pathways
    Activation of Innate immune Response, Transition Metal Ion Homeostasis
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