P4HTM antibody (AA 201-300) (HRP)

Catalog No. ABIN735677

Product Details anti-P4HTM Antibody (HRP)

Target: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Binding Specificity: AA 201-300

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P4HTM antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PH-4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for P4HTM

Target: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Alternative Name: P4HTM (P4HTM Products)

Synonyms: Ph-4 antibody, RGD1311848 antibody, EGLN4 antibody, HIFPH4 antibody, P4H-TM antibody, PH-4 antibody, PH4 antibody, PHD4 antibody, 4933406E20Rik antibody, AI853847 antibody, BB128974 antibody, prolyl 4-hydroxylase, transmembrane antibody, prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) antibody, shisa family member 5 antibody, P4htm antibody, P4HTM antibody, SHISA5 antibody

Background:

Synonyms: Transmembrane prolyl 4-hydroxylase, Proline hydrolase 4, proline 4-hydroxylase, P4htm, hypoxia-inducible factor prolyl 4-hydroxylase, P4H-TM, H-prolyl hydroxylase PH-4, P4HTM_HUMAN, Hypoxia-inducible factor prolyl hydroxylase 4, H-PH4, H-prolyl hydroxylase 4, HPH-4, transmembrane prolyl 4-hydroxylase isoform a, P4HTM, EGLN4, HPH4, P4H-TM, PH-4, PH4, PHD4, P4H with transmembrane domain, Prolyl hydroxlase domain-containing 4, hypoxia inducible factor prolyl 4 hydroxylase, H-prolyl hydroxylase 4.

Background: The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].