Caspase 6 antibody (pSer257) (Cy3)
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- Target See all Caspase 6 (CASP6) Antibodies
- Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
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Binding Specificity
- pSer257
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Caspase 6 antibody is conjugated to Cy3
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)
- Cross-Reactivity
- Mouse
- Predicted Reactivity
- Human,Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human Caspase 6 around the phosphorylation site of Ser257
- Isotype
- IgG
- Top Product
- Discover our top product CASP6 Primary Antibody
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- Application Notes
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
- Alternative Name
- Caspase 6 (CASP6 Products)
- Synonyms
- xCaspase-6 antibody, mch2 antibody, caspase-6 antibody, zgc:112960 antibody, CASP6 antibody, casp6 antibody, Mch2 antibody, mCASP-6 antibody, MCH2 antibody, caspase 6 L homeolog antibody, caspase 6 antibody, caspase 6, apoptosis-related cysteine peptidase antibody, group XIIA secretory phospholipase A2 antibody, caspase-6 antibody, casp6.L antibody, casp6 antibody, CASP6 antibody, CpipJ_CPIJ017008 antibody, Casp6 antibody
- Background
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Synonyms: Apoptosis-related cysteine protein, Apoptosis Related Cysteine Protease, Apoptotic cysteine protease MCH2, Apoptotic protease MCH 2, Apoptotic protease MCH2, Casp 6, Casp6, Caspase 6 apoptosis related cysteine protease, Caspase 6 precursor, Caspase6, Human cysteine protease Mch2 isoform alpha, Mch 2, Mch2, CASP6_HUMAN.
Background: Caspase-6 is involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. Subunit is compose of heterodimer of a18 kDa (p18) and a 11 kDa (p11) subunit. Subcellular location at cytoplasmic. Cleavages by CPP32, caspase-8 or -10 generate the two active subunits. It belongs to the peptidase C14 family.
- Gene ID
- 839
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis
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