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ARNTL antibody (AA 569-573)
ARNTL
Reactivity: Human, Rat, Mouse
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ARNTL Antibody
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Target
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ARNTL
(Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))
Binding Specificity
All epitopes for ARNTL antibodies
AA 569-573
Reactivity
All reactivities for ARNTL antibodies
Human, Rat, Mouse
Host
All hosts for ARNTL antibodies
Rabbit
Clonality
All clonalities for ARNTL antibodies
Polyclonal
Conjugate
All conjugates for ARNTL antibodies
This ARNTL antibody is un-conjugated
Application
All applications for ARNTL antibodies
Western Blotting (WB)
Sequence
S-S-S-I-L
Specificity
This antibody detects endogenous level of total BMAL1 protein.
Cross-Reactivity (Details)
Species reactivity (expected):Human, Mouse, Rat
Purification
Affinity-chromatography using epitope-specific peptide
Immunogen
Peptide sequence around aa.569~573 derived from Human BMAL1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store (in aliquots) at -20 °C.
Target Details for ARNTL
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Target
ARNTL
(Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))
Alternative Name
ARNTL / BMAL1 (ARNTL Products )
Synonyms
BMAL1 antibody, BMAL1c antibody, JAP3 antibody, MOP3 antibody, PASD3 antibody, TIC antibody, bHLHe5 antibody, Bmal1 antibody, ARNTL antibody, xBmal1 antibody, arntl antibody, Arnt3 antibody, BMAL1b antibody, bmal1b' antibody, aryl hydrocarbon receptor nuclear translocator like antibody, aryl hydrocarbon receptor nuclear translocator-like antibody, aryl hydrocarbon receptor nuclear translocator like S homeolog antibody, ARNTL antibody, Arntl antibody, arntl.S antibody, arntl antibody
Background
ARNTL-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins.Synonyms: Aryl hydrocarbon receptor nuclear translocator-like protein 1, BHLHE5, Basic-helix-loop-helix-PAS protein MOP3, Brain and muscle ARNT-like 1, Class E basic helix-loop-helix protein 5, MOP3, Member of PAS protein 3, PAS domain-containing protein 3, PASD3, bHLH-PAS protein JAP3, bHLHe5
Molecular Weight
69 kDa
Gene ID
406
NCBI Accession
NP_001025443
UniProt
O00327
Pathways
Regulation of Lipid Metabolism by PPARalpha , Protein targeting to Nucleus , Warburg Effect
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