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ESRP1 antibody (N-Term)

ESRP1 Reactivity: Human, Mouse, Rat WB, IHC (p), IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783405
  • Target See all ESRP1 Antibodies
    ESRP1 (Epithelial Splicing Regulatory Protein 1 (ESRP1))
    Binding Specificity
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 22
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 20
    • 4
    Rabbit
    Clonality
    • 22
    • 2
    Polyclonal
    Conjugate
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ESRP1 antibody is un-conjugated
    Application
    • 17
    • 8
    • 7
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects ESRP1 / RBM35A at N-term. It is predicted to not cross-react with other RBM35/ESRP family members. At least five isoforms of RBM35A are known to exist, this antibody will detect all five.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, Mouse, Rat.
    Purification
    Affinity Chromatography purified via peptide column
    Immunogen
    12 amino acid peptide near the amino terminus of Human RBM35A
    Top Product
    Discover our top product ESRP1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, 0.02 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    ESRP1 (Epithelial Splicing Regulatory Protein 1 (ESRP1))
    Alternative Name
    ESRP1 / RBM35A (ESRP1 Products)
    Synonyms
    rbm35a antibody, RBM35A antibody, RMB35A antibody, 2210008M09Rik antibody, A630065D16 antibody, BC031468 antibody, Rbm35a antibody, RGD1560481 antibody, wu:fi28a07 antibody, zgc:154050 antibody, epithelial splicing regulatory protein 1 antibody, epithelial splicing regulatory protein 1 L homeolog antibody, ESRP1 antibody, esrp1.L antibody, Esrp1 antibody, esrp1 antibody
    Background
    RBM35A, also known as ESRP1, is a mRNA splicing factor that with its related protein RBM35B (ESRP2) are coordinators of an epithelial cell-type-specific splicing program. RBM35A contains three putative RNA recognition motifs and acts by directly binding specific sequences in mRNAs. RBM35A is involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs. Other recent studies have shown that RMB35A may also act as a novel tumor suppressor.Synonyms: Epithelial splicing regulatory protein 1, RNA-binding motif protein 35A, RNA-binding protein 35A
    Gene ID
    54845
    NCBI Accession
    NP_001030087
    UniProt
    Q6NXG1
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