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PRR5 antibody (C-Term)
PRR5
Reactivity: Human, Mouse, Rat
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PRR5 Antibody
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Target
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PRR5
(Proline Rich 5 (Renal) (PRR5))
Binding Specificity
All epitopes for PRR5 antibodies
C-Term
Reactivity
All reactivities for PRR5 antibodies
Human, Mouse, Rat
Host
All hosts for PRR5 antibodies
Rabbit
Clonality
All clonalities for PRR5 antibodies
Polyclonal
Conjugate
All conjugates for PRR5 antibodies
This PRR5 antibody is un-conjugated
Application
All applications for PRR5 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody detects PRR5 at C-term. PRR5 antibody is predicted to not cross-react with other Protor protein family members.
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse, rat
Purification
Affinity chromatography purified via peptide column
Immunogen
20 amino acid peptide near the carboxy terminus of human PRR5
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
PBS containing 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Target Details for PRR5
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Target
PRR5
(Proline Rich 5 (Renal) (PRR5))
Alternative Name
PRR5 (PRR5 Products )
Synonyms
AU043908 antibody, Arhgap8 antibody, C030017C09Rik antibody, C78947 antibody, Protor-1 antibody, Protor1 antibody, FLJ20185k antibody, PP610 antibody, PROTOR-1 antibody, PROTOR1 antibody, pp610 antibody, protor1 antibody, protor2 antibody, proline rich 5 (renal) antibody, proline rich 5 antibody, proline rich 5 L homeolog antibody, Prr5 antibody, PRR5 antibody, prr5.L antibody
Background
Proline-rich protein 5 (PRR5), also known as Protor-1, is a 388 amino acid protein in Protor family, is thought to act as a tumor suppressor in breast and colorectal tumorigenesis. PRR5 is widely expressed and possesses two RICTOR interaction sites and a C-terminal Proline rich region. It promotes Rapamycin complex 2 (mTORC2) activity. There are four isoforms of PRR5 that are produced as a result of alternative splicing events and these isoforms play an important role in the modulation of platelet-derived growth factor signaling and in the regulation of PDGFR-β expression.Synonyms: PROTOR1, Proline-rich protein 5, Protein observed with Rictor-1, Protor-1
Gene ID
55615
NCBI Accession
NP_001017528
UniProt
P85299
Pathways
PI3K-Akt Signaling
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