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ZMIZ2 antibody (Center)
ZMIZ2
Reactivity: Human, Mouse
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ZMIZ2 Antibody
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Target
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ZMIZ2
(Zinc Finger, MIZ-Type Containing 2 (ZMIZ2))
Binding Specificity
All epitopes for ZMIZ2 antibodies
Center
Reactivity
All reactivities for ZMIZ2 antibodies
Human, Mouse
Host
All hosts for ZMIZ2 antibodies
Rabbit
Clonality
All clonalities for ZMIZ2 antibodies
Polyclonal
Conjugate
All conjugates for ZMIZ2 antibodies
This ZMIZ2 antibody is un-conjugated
Application
All applications for ZMIZ2 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody detects ZMIZ2 at Center. ZIMP7 antibody is predicted to not cross-react with other PIAS protein family members.
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse
Purification
Affinity chromatography purified via peptide column
Immunogen
17 amino acid peptide near the center of human ZIMP7
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
PBS containing 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Target Details for ZMIZ2
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Target
ZMIZ2
(Zinc Finger, MIZ-Type Containing 2 (ZMIZ2))
Alternative Name
ZMIZ2 (ZMIZ2 Products )
Synonyms
MGC86475 antibody, RGD1309256 antibody, zimp7 antibody, hzimp7 antibody, NET27 antibody, TRAFIP20 antibody, ZIMP7 antibody, hZIMP7 antibody, 2410117E06Rik antibody, D11Bwg0280e antibody, R74931 antibody, Zimp7 antibody, zinc finger, MIZ-type containing 2 S homeolog antibody, zinc finger, MIZ-type containing 2 antibody, zinc finger MIZ-type containing 2 antibody, zmiz2.S antibody, ZMIZ2 antibody, zmiz2 antibody, Zmiz2 antibody
Background
ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification. At least four isoforms are known to exist.Synonyms: HRIHFB2007, KIAA1886, ZIMP7, Zinc finger MIZ domain-containing protein 2
Gene ID
83637
NCBI Accession
NP_113637
UniProt
Q8NF64
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