ZMIZ1 antibody (N-Term)
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- Target See all ZMIZ1 Antibodies
- ZMIZ1 (Zinc Finger, MIZ-Type Containing 1 (ZMIZ1))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ZMIZ1 antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- This antibody detects ZMIZ1 / RAI17 at N-term. At least three isoforms are known to exist, this antibody will recognize all three. ZIMP10 antibody is predicted to not cross-react with other PIAS protein family members.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- 15 amino acid peptide near the amino terminus of human ZIMP10
- Top Product
- Discover our top product ZMIZ1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- Target
- ZMIZ1 (Zinc Finger, MIZ-Type Containing 1 (ZMIZ1))
- Alternative Name
- ZMIZ1 / RAI17 (ZMIZ1 Products)
- Synonyms
- miz antibody, rai17 antibody, zimz1 antibody, zimp10 antibody, hzimp10 antibody, MIZ antibody, RAI17 antibody, TRAFIP10 antibody, ZIMP10 antibody, hZIMP10 antibody, BC065120 antibody, E330020C23 antibody, ENSMUSG00000072684 antibody, Gm10397 antibody, I920194n01 antibody, Rai17 antibody, Zimp10 antibody, wu:fb80e10 antibody, zgc:175159 antibody, zmiz1 antibody, zinc finger MIZ-type containing 1 antibody, zinc finger, MIZ-type containing 1 antibody, zinc finger, MIZ-type containing 1a antibody, ZMIZ1 antibody, zmiz1 antibody, Zmiz1 antibody, zmiz1a antibody
- Background
- ZIMP10, also known as ZMIZ1, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein initially identified as a transcriptional co-activator of the androgen receptor (AR). ZIMP10 and the related protein ZIMP7 interact with PIAS3 and enhances AR-mediated transcription. Later experiments showed that ZIMP10 is also a co-activator of the p53 tumor suppressor. Mice deficient in ZIMP10 result in embryonic lethality by E10.5, these embryos reveal severe defects in the reorganization of the yolk sac vascular plexus, indicating that ZIMP10 plays an important role in proper vascular development.Synonyms: KIAA1224, PIAS-like protein Zimp10, Retinoic acid-induced protein 17, ZIMP10, Zinc finger MIZ domain-containing protein 1
- Gene ID
- 57178
- NCBI Accession
- NP_065071
- UniProt
- Q9ULJ6
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