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Angiotensin II Type-1 Receptor antibody (Center)

AGTR1 Reactivity: Human, Rat, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783580
  • Target See all Angiotensin II Type-1 Receptor (AGTR1) Antibodies
    Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))
    Binding Specificity
    • 16
    • 9
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 49
    • 22
    • 20
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 47
    • 3
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 51
    • 3
    Polyclonal
    Conjugate
    • 32
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Angiotensin II Type-1 Receptor antibody is un-conjugated
    Application
    • 31
    • 23
    • 17
    • 15
    • 13
    • 10
    • 9
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects Type-1 angiotensin II receptor (AT1) at Center.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    16 amino acid peptide from near the center of human AGTR1
    Top Product
    Discover our top product AGTR1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))
    Alternative Name
    Type-1 Angiotensin II Receptor (AT1) (AGTR1 Products)
    Synonyms
    AG2S antibody, AGTR1A antibody, AGTR1B antibody, AT1 antibody, AT1AR antibody, AT1B antibody, AT1BR antibody, AT1R antibody, AT2R1 antibody, AT2R1A antibody, AT2R1B antibody, HAT1R antibody, 1810074K20Rik antibody, AI551199 antibody, AT1a antibody, Agtr-1a antibody, Agtr1 antibody, Angtr-1a antibody, AT1A antibody, XAT-1 antibody, agtr1-A antibody, agtr1.2 antibody, AT1-R antibody, at1 antibody, AGTR1 antibody, Agtr-1b antibody, Angtr-1b antibody, agtr1 antibody, agtr1-a antibody, agtr1-b antibody, xAT antibody, angiotensin II receptor type 1 antibody, angiotensin II receptor, type 1a antibody, angiotensin II receptor type 1 S homeolog antibody, uncharacterized AGTR1 antibody, angiotensin II receptor, type 1b antibody, angiotensin II receptor type 1 L homeolog antibody, AGTR1 antibody, Agtr1a antibody, agtr1.S antibody, Agtr1 antibody, Agtr1b antibody, agtr1.L antibody
    Background
    Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. AGTR1, the type 1 receptor, is thought to mediate the major cardiovascular effects of angiotensin II and may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. AGTR1 has recently been found to regulate the differentiation of bone marrow-derived monocyte lineage progenitors from hematopoietic stem cells, indicating the diversity of the roles of AGTR1.Synonyms: AGTR1, AGTR1A, AGTR1B, AT1AR, AT1BR, AT2R1, AT2R1B
    Gene ID
    185
    NCBI Accession
    NP_000676
    UniProt
    P30556
    Pathways
    JAK-STAT Signaling, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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