Smooth Muscle Actin antibody (N-Term)

Catalog No. ABIN783900

The Rabbit Polyclonal anti-Smooth Muscle Actin antibody (ABIN783900) specifically detects Smooth Muscle Actin in IHC (p). The antibody is reactive with Human, Rat, Mouse, Chicken, Rabbit, Cow and Monkey samples.

Quick Overview for Smooth Muscle Actin antibody (N-Term) (ABIN783900)

Target: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Reactivity: Human, Rat, Mouse, Chicken, Rabbit, Cow, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Smooth Muscle Actin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Smooth Muscle Actin Antibody

Binding Specificity: N-Term

Specificity: This antibody stains smooth muscle cells in vessel walls, gut wall, and myometrium. Myoepithelial cells in breast and salivary gland are also stained. It reacts with tumors arising from smooth muscles and myoepithelial cells. Actin from fibroblasts (beta- and gamma-cytoplasmic), striated muscle (alpha-sarcomeric), and myocardium (alpha-myocardial) are not labeled.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Rabbit, Chicken, Bovine and Baboon.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogen: A synthetic peptide from N-terminus of Human alpha smooth muscle isoform of Actin Genename: ACTA2

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM PBS, pH 7.4, 0.09 % Sodium Azide, BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Target Details for Smooth Muscle Actin

Target: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Background: Actin alpha 2, the human aortic smooth muscle actin gene, is one of six different actin isoforms which have been identified. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus.Synonyms: ACTSA, ACTVS, Alpha-actin-2, Cell growth-inhibiting gene 46 protein

Gene ID: 59

NCBI Accession: NP_001135417

Pathways: Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development