Claudin 18 (CLDN18) (Middle Region) antibody

Details for Product No. ABIN785154
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Antigen
Synonyms claudin-18, CLDN18, SFTA5, SFTPJ
Epitope
Middle Region
(13), (8), (3), (2), (2), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Human
(22), (6), (5), (2), (2), (2)
Host
Rabbit
(22), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(23), (10), (10), (2), (2), (2), (1)
Pubmed 1 reference available
Quantity 50 µg
Options
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Catalog No. ABIN785154
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human CLDN18
Sequence LVTNFWMSTA NMYTGMGGMV QTVQTRYTFG AALFVGWVAG GLTLIGGVMM
Predicted Reactivity Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, African clawed frog : 90 %, Dog : 90 %, Chicken : 70 %
Characteristics This is a rabbit polyclonal antibody against CLDN18. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name CLDN18
Background CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells.
Molecular Weight 28 kDa
Gene ID 51208
NCBI Accession NP_001002026, NM_001002026
UniProt P56856
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 261 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Claudin 18 (CLDN18) (Middle Region) antibody WB Suggested Anti-CLDN18 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: THP-1 cell lysate
anti-Claudin 18 (CLDN18) (Middle Region) antibody (2) WB Suggested Anti-CLDN18
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:12500
Positive Control: THP-1 cell lysate
Background publications Karanjawala, Illei, Ashfaq et al.: "New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8." in: The American journal of surgical pathology, Vol. 32, Issue 2, pp. 188-96, 2008 (PubMed).

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