IARS antibody (Middle Region)
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- Target See all IARS Antibodies
- IARS (Isoleucyl-tRNA Synthetase (IARS))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IARS antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- YEAAKVFGLR SRKLKLFLNE TQTQEITEDI PVKTLNMKTV YVSVLPTTAD
- Predicted Reactivity
- Cow: 85%, Dog: 85%, Guinea Pig: 93%, Horse: 85%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against IARS. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human IARS
- Top Product
- Discover our top product IARS Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1262 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- IARS (Isoleucyl-tRNA Synthetase (IARS))
- Alternative Name
- IARS (IARS Products)
- Synonyms
- fi46h05 antibody, zgc:63790 antibody, wu:fi46h05 antibody, K19E20.18 antibody, K19E20_18 antibody, ovule abortion 2 antibody, ECK0027 antibody, ilvS antibody, JW0024 antibody, An08g06770 antibody, AO090012000505 antibody, 2510016L12Rik antibody, AI327140 antibody, AU044614 antibody, E430001P04Rik antibody, ILRS antibody, Iarsl antibody, IARS1 antibody, ILERS antibody, IRS antibody, PRO0785 antibody, isoleucyl-tRNA synthetase antibody, tRNA synthetase class I (I, L, M and V) family protein antibody, isoleucine--tRNA ligase antibody, isoleucyl-tRNA synthetase, cytoplasmic antibody, isoleucine-tRNA synthetase antibody, iars antibody, IARS antibody, OVA2 antibody, ileS antibody, MBAR_RS19160 antibody, Rmag_0340 antibody, ANI_1_964074 antibody, CHLREDRAFT_106327 antibody, EDI_049880 antibody, OE_RS08520 antibody, AOR_1_1912194 antibody, Iars antibody
- Background
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Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.
Alias Symbols: FLJ20736, IARS1, ILRS, PRO0785, IRS, ILERS
Protein Interaction Partner: UBC, MDM2, SART3, AURKA, SUMO2, SUMO3, STAU1, LGR4, AIMP2, RPLP0, RPL38, RPL24, RPL23A, RPL18, RPL15, QARS, NMT1, MARS, MAP4, HNRNPA2B1, EPRS, DARS, AIMP1, HNRNPUL2, LARS, RPS27L, IGF2BP3, SYNCRIP, EEF1E1, FBXO6, EGFR, UBD, ITGA4, FN1, METTL18, gag, VCAM1
Protein Size: 1262 - Molecular Weight
- 144 kDa
- Gene ID
- 3376
- NCBI Accession
- NM_013417, NP_038203
- UniProt
- P41252
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