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Osteoprotegerin antibody
TNFRSF11B
Reactivity: Human
WB, ELISA, IF, FACS
Host: Mouse
Monoclonal
5G2
unconjugated
Product Details anti-Osteoprotegerin Antibody
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Target
See all Osteoprotegerin (TNFRSF11B) Antibodies
Osteoprotegerin (TNFRSF11B)
(Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
Reactivity
All reactivities for Osteoprotegerin antibodies
Human
Host
All hosts for Osteoprotegerin antibodies
Mouse
Clonality
All clonalities for Osteoprotegerin antibodies
Monoclonal
Conjugate
All conjugates for Osteoprotegerin antibodies
This Osteoprotegerin antibody is un-conjugated
Application
All applications for Osteoprotegerin antibodies
Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
Purification
Ascitic fluid
Immunogen
Purified recombinant fragment of human TNFRSF11B expressed in E. Coli.
Clone
5G2
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
WB: 1/500 - 1/2000, IF: 1/200 - 1/1000, FC: 1/200-1/400, ELISA: Propose dilution 1/10000.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
100g/100l
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Target Details for Osteoprotegerin
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Target
Osteoprotegerin (TNFRSF11B)
(Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
Alternative Name
TNFRSF11B (TNFRSF11B Products )
Synonyms
CD254 antibody, ODF antibody, OPGL antibody, OPTB2 antibody, RANKL antibody, TRANCE antibody, hRANKL2 antibody, sOdf antibody, OCIF antibody, OPG antibody, TR1 antibody, Opg antibody, ocif antibody, opg antibody, tr1 antibody, TNF superfamily member 11 antibody, TNF receptor superfamily member 11b antibody, tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) antibody, TNF receptor superfamily member 11B antibody, tumor necrosis factor receptor superfamily member 11b S homeolog antibody, tumor necrosis factor receptor superfamily, member 11b antibody, TNFSF11 antibody, TNFRSF11B antibody, Tnfrsf11b antibody, tnfrsf11b.S antibody
Target Type
Chemical
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. Synonyms: OPG, TR1, OCIF, MGC29565, TNFRSF11B
Molecular Weight
60kDa
Gene ID
4982
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