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MAP2K5 antibody (pThr315)
MAP2K5
Reactivity: Human, Mouse, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MAP2K5 Antibody
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Target
See all MAP2K5 Antibodies
MAP2K5
(Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))
Binding Specificity
All epitopes for MAP2K5 antibodies
pThr315
Reactivity
All reactivities for MAP2K5 antibodies
Human, Mouse, Rat
Host
All hosts for MAP2K5 antibodies
Rabbit
Clonality
All clonalities for MAP2K5 antibodies
Polyclonal
Conjugate
All conjugates for MAP2K5 antibodies
This MAP2K5 antibody is un-conjugated
Application
All applications for MAP2K5 antibodies
Western Blotting (WB)
Specificity
The antibody detects endogenous level of MEK5 only when phosphorylated at serine 311 or threonine 315.
Purification
Affinity purified
Immunogen
Peptide sequence around phosphorylation site of pSerine 311 and pThr315 (V-N-S (p) I-A-K-T (p) -Y-V) derived from Rat MEK5. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
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Alternatives
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Application Details
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Application Notes
Western blotting: 1:500-1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target Details for MAP2K5
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Target
MAP2K5
(Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))
Alternative Name
MEK5 (MAP2K5 Products )
Synonyms
Mek5 antibody, HsT17454 antibody, MAPKK5 antibody, MEK5 antibody, PRKMK5 antibody, AI324775 antibody, AI428457 antibody, Mapkk5 antibody, Prkmk5 antibody, fb73f02 antibody, wu:fb73f02 antibody, zgc:172137 antibody, ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 antibody, ATMAP2K_ALPHA antibody, ATMEK5 antibody, ATMKK5 antibody, MAP KINASE KINASE 5 antibody, MAP kinase kinase 5 antibody, MAP2K_A antibody, mitogen activated protein kinase kinase 5 antibody, mitogen-activated protein kinase kinase 5 antibody, mitogen-activated protein kinase kinase 5 L homeolog antibody, MAP kinase kinase 5 antibody, Map2k5 antibody, MAP2K5 antibody, map2k5 antibody, map2k5.L antibody, MKK5 antibody
Background
Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis.
Molecular Weight
46 kDa
Gene ID
29568
NCBI Accession
NP_001029
UniProt
Q62862
Pathways
MAPK Signaling , Neurotrophin Signaling Pathway
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