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Transglutaminase 4 (Prostate) (TGM4) (AA 13-17) antibody

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Antigen
Epitope
AA 13-17
15
12
12
11
9
7
3
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
85
1
1
Host
Rabbit
53
19
13
Clonality
Polyclonal
Conjugate
Un-conjugated
5
5
5
3
3
3
Application
Western Blotting (WB)
73
50
40
17
7
5
4
2
1
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Immunogen Peptide sequence around AA 13-17 (E-L-K-V-F) derived from Human DP-1 Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Specificity The antibody detects endogenous levels of total DP-1 protein.
Purification Affinity purified
Alternative Name DP-1 (TGM4 Antibody Abstract)
Background Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis.
Molecular Weight 45 kDa
Gene ID 7027
NCBI Accession NP_009042
UniProt Q14186
Pathways
Application Notes Western blotting: 1:500-1:1000  
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Background publications Wu, Zukerberg, Ngwu et al.: "In vivo association of E2F and DP family proteins." in: Molecular and cellular biology, Vol. 15, Issue 5, pp. 2536-46, 1995 (PubMed).