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MME antibody (AA 6-10)

MME Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated

Catalog No. ABIN871686

Datasheet as PDF

Target See all MME Antibodies

MME (Membrane Metallo-Endopeptidase (MME))
Binding Specificity
16

14

9

8

8

7

7

7

6

6

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 6-10
Reactivity
201

57

50

3

2

2

2

2

2

1

1

1

1
Human, Mouse, Rat
Host
109

97

2
Rabbit
Compatible Secondaries
Clonality
105

102

2
Polyclonal
Conjugate
104

19

17

13

9

6

4

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This MME antibody is un-conjugated
Application
131

92

78

67

35

27

20

20

13

13

10

8

5

5

5

3

2

1

1

1
Western Blotting (WB)

Specificity

The antibody detects endogenous level of total CD10 protein.

Purification

Affinity purified

Immunogen

Peptide sequence around AA 6-10 (S-Q-M-D-I) derived from Human CD10. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

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anti-Membrane Metallo-Endopeptidase (MME) (AA 52-246) antibody
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anti-Membrane Metallo-Endopeptidase (MME) (AA 52-352) antibody
MME Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 382-538) antibody
MME Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 501-600) antibody
MME Reactivity: Human, Mouse, Rat FACS, WB, ELISA, ICC, IHC (p), IHC (fro), IF (p), IF (cc) Host: Rabbit Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibody
MME Reactivity: Human WB, IHC, StM Host: Mouse Monoclonal MME-1870 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 286-428) antibody
MME Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) antibody (FITC)
MME Reactivity: Human FACS Host: Mouse Monoclonal MEM-78 FITC

anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibody
MME Reactivity: Human FACS, WB, IHC, ELISA, ICC, Neut Host: Mouse Monoclonal 6G12E12 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibody
MME Reactivity: Human WB, IHC, ELISA, StM, Coat Host: Mouse Monoclonal MME-1892 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 52-750) antibody
MME Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

Application Notes

Western blotting: 1:500

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative

Sodium azide

Precaution of Use

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C/-20 °C

Storage Comment

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target

MME (Membrane Metallo-Endopeptidase (MME))

Alternative Name

CD10 (MME Products)

Synonyms

CALLA antibody, CD10 antibody, NEP antibody, SFE antibody, 6030454K05Rik antibody, C85356 antibody, Nep antibody, neprilysin antibody, membrane metalloendopeptidase antibody, membrane metallo endopeptidase antibody, membrane metallo-endopeptidase antibody, MME antibody, Mme antibody

Target Type

Chemical

Background

Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.

Molecular Weight

100 kDa

Gene ID

4311

NCBI Accession

NP_000893

UniProt

P08473

Pathways

RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration