PRKD3 antibody (pSer41) (AbBy Fluor® 555)

Catalog No. ABIN877283

Product Details anti-PRKD3 Antibody (AbBy Fluor® 555)

Target: PRKD3 (Protein Kinase D3 (PRKD3))

Binding Specificity: pSer41

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKD3 antibody is conjugated to AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human PRKD3 around the phosphorylation site of Ser41 [RL(p-S)NG]

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PRKD3

Target: PRKD3 (Protein Kinase D3 (PRKD3))

Alternative Name: PRKD3 (PRKD3 Products)

Synonyms: EPK2 antibody, PKC-NU antibody, PKD3 antibody, PRKCN antibody, nPKC-NU antibody, PRKD3 antibody, 4930557O20Rik antibody, 5730497N19Rik antibody, Pkcnu antibody, Prkcn antibody, protein kinase D3 antibody, PRKD3 antibody, prkd3 antibody, Prkd3 antibody

Background:

Synonyms: PRKD3phospho S41, PKD/PKC_Phospho-Ser41, EPK 2, EPK2, EPK-2, nPKC nu, nPKCnu, nu, PKCnu, PKD 3, PKD3, PRK D3, PRKCN, PRKD 3, PRKD3, Protein kinase C, Protein kinase C nu, Protein kinase C nu type, Protein kinase D3, Protein kinase EPK 2, Protein kinase EPK2, Serine threonine protein kinase, Serine/threonine protein kinase D3.

Background: Protein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.