CDCA2 antibody (AA 361-450) (HRP)

Catalog No. ABIN889653

Product Details anti-CDCA2 Antibody (HRP)

Target: CDCA2 (Cell Division Cycle Associated 2 (CDCA2))

Binding Specificity: AA 361-450

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCA2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CDCA2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CDCA2

Target: CDCA2 (Cell Division Cycle Associated 2 (CDCA2))

Alternative Name: CDCA2 (CDCA2 Products)

Synonyms: fc32e05 antibody, wu:fc32e05 antibody, wu:fi04h07 antibody, Repo-Man antibody, 2610311M19Rik antibody, AI586158 antibody, cell division cycle associated 2 antibody, si:ch211-244o22.2 antibody, CDCA2 antibody, si:ch211-244o22.2 antibody, Cdca2 antibody

Background:

Synonyms: PPP1R81, Repo-Man, Cell division cycle-associated protein 2, Recruits PP1 onto mitotic chromatin at anaphase protein, CDCA2

Background: Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.

Gene ID: 157313

UniProt: Q69YH5