CDCA2 antibody (AA 361-450)

Catalog No. ABIN872339

The Rabbit Polyclonal anti-CDCA2 antibody is suitable to detect CDCA2 in samples from Human. It has been validated for WB, IF (cc), IF (p), IHC (p) and IHC (fro).

Quick Overview for CDCA2 antibody (AA 361-450) (ABIN872339)

Target: CDCA2 (Cell Division Cycle Associated 2 (CDCA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CDCA2 Antibody

Binding Specificity: AA 361-450

Purpose: CDCA2 Polyclonal Antibody

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CDCA2

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CDCA2

Target: CDCA2 (Cell Division Cycle Associated 2 (CDCA2))

Alternative Name: CDCA2

Background:

Synonyms: PPP1R81, Repo-Man, Cell division cycle-associated protein 2, Recruits PP1 onto mitotic chromatin at anaphase protein, CDCA2

Background: Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.

Gene ID: 157313

UniProt: Q69YH5