CDCA2 antibody (Internal Region)

Catalog No. ABIN6258502

The Rabbit Polyclonal anti-CDCA2 antibody (ABIN6258502) specifically detects CDCA2 in WB, IHC, IF and ICC. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for CDCA2 antibody (Internal Region) (ABIN6258502)

Target: CDCA2 (Cell Division Cycle Associated 2 (CDCA2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-CDCA2 Antibody

Binding Specificity: Internal Region

Purpose: CDCA2 Antibody

Specificity: CDCA2 Antibody detects endogenous levels of total CDCA2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CDCA2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CDCA2

Target: CDCA2 (Cell Division Cycle Associated 2 (CDCA2))

Alternative Name: CDCA2

Background:

Description: Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.

Gene: CDCA2

Molecular Weight: 113 kDa

Gene ID: 157313

UniProt: Q69YH5