CNIH2, CNIH3 (AA 25-120) antibody (Biotin)
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- Target
- CNIH2, CNIH3
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Binding Specificity
- AA 25-120
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Biotin
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- This antibody detects both CNIH2 and CNIH3 proteins
- Cross-Reactivity
- Rat
- Predicted Reactivity
- Human,Mouse,Dog,Cow,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CNIH2/CNIH3
- Isotype
- IgG
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- CNIH2, CNIH3
- Alternative Name
- CNIH2/3
- Background
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Synonyms: Protein cornichon homolog 2, CNIH2, Cornichon family AMPA receptor auxiliary protein 2, Protein cornichon homolog 3, CNIH3, Cornichon family AMPA receptor auxiliary protein 3
Background: CNIH2 and CNIH3 regulate the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). They promote their targeting to the cell membrane and synapses and modulate their gating properties by regulating their rates of activation, deactivation and desensitization. CNIH2 also blocks CACNG8-mediated resensitization of AMPA receptors.
- Gene ID
- 254263, 149111
- UniProt
- Q6PI25, Q8TBE1
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