PTPN1 antibody (AA 1-100) (AbBy Fluor® 647)
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- Target See all PTPN1 Antibodies
- PTPN1 (Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1))
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Binding Specificity
- AA 1-100
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PTPN1 antibody is conjugated to AbBy Fluor® 647
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Predicted Reactivity
- Cow,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PTP-1B
- Isotype
- IgG
- Top Product
- Discover our top product PTPN1 Primary Antibody
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- Application Notes
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PTPN1 (Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1))
- Alternative Name
- PTP1B (PTPN1 Products)
- Synonyms
- PTPN1 antibody, PTP1B antibody, PTP-1B antibody, PTP-HA2 antibody, Ptp antibody, ptp1b antibody, wu:fk54h03 antibody, CPTP1 antibody, protein tyrosine phosphatase, non-receptor type 1 antibody, protein tyrosine phosphatase, non-receptor type 1 L homeolog antibody, PTPN1 antibody, Ptpn1 antibody, ptpn1 antibody, ptpn1.L antibody
- Background
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Synonyms: PTP1B, Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine phosphatase 1B, PTP-1B, PTPN1
Background: Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK, inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
- Gene ID
- 5770
- UniProt
- P18031
- Pathways
- TLR Signaling, Response to Growth Hormone Stimulus, ER-Nucleus Signaling, Platelet-derived growth Factor Receptor Signaling
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