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PVRL2 antibody

PVRL2 Reactivity: Human, Mouse WB, FACS, IHC, IP Host: Rat Monoclonal 502-57 unconjugated
Catalog No. ABIN920706
  • Target See all PVRL2 Antibodies
    PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
    Reactivity
    • 70
    • 24
    • 13
    • 4
    • 2
    • 1
    Human, Mouse
    Host
    • 52
    • 14
    • 10
    Rat
    Clonality
    • 43
    • 32
    • 1
    Monoclonal
    Conjugate
    • 36
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PVRL2 antibody is un-conjugated
    Application
    • 51
    • 37
    • 17
    • 15
    • 15
    • 14
    • 14
    • 11
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Specificity
    Reacts with nectin-2.
    Purification
    Purified
    Immunogen
    The extracellular domain of mouse nectin-2.
    Clone
    502-57
    Isotype
    IgG2a
    Top Product
    Discover our top product PVRL2 Primary Antibody
  • Application Notes
    Immunohistochemistry: (frozen sections) Use at a 1:10 dilution. Flow cytometry: Use at a 1:10 dilution. Western blot: Use at a 1:10 dilution. Fixation with PFA or acetone/methanol is recommended.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    1 mL of 100 µg/mL
    Storage
    4 °C
  • Target
    PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
    Alternative Name
    Nectin-2 (PVRL2 Products)
    Synonyms
    prr2 antibody, AI325026 antibody, AI987993 antibody, Cd112 antibody, MPH antibody, Pvr antibody, Pvs antibody, nectin-2 antibody, CD112 antibody, HVEB antibody, PRR2 antibody, PVRR2 antibody, nectin cell adhesion molecule 2 antibody, Nectin2 antibody, NECTIN2 antibody
    Background
    Nectin (originally isolated as poliovirus receptor- related protein (PRR)) is a cell-cell adhesion molecule of the immunoglobulin supergene family. Nectin is co-localized with afadin at cadherin-based cell-cell adherence juctions in various tissues and cell lines. The nectin family consists of nectin-1, nectin-2 and nectin-3. Nectin-2 is a plasma membrane adhesion molecule localized at adherens junctions which is widely expressed in various cells lines including neuronal, endothelial, epithelial and hematopoietic cells. Next to its role in adherens junctions it functions as alphaherpus virus receptor and acts also as intercellular adhesion molecule and pseudorabies virus receptor. Disruption of mouse nectin-2 leads to infertility of male mice. Synonyms: PRR2, CD112
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization
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