PHF1 antibody

Catalog No. ABIN931204

Product Details anti-PHF1 Antibody

Target: PHF1 (PHD Finger Protein 1 (PHF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PHF1 antibody is un-conjugated

Application: Dot Blot (DB)

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: PHF1 antibody was raised in mouse using recombinant Human Phd Finger 1 (Phf1)

Clone: 864C6a

Isotype: IgG1

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: PHF1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for PHF1

Target: PHF1 (PHD Finger Protein 1 (PHF1))

Alternative Name: PHF1 (PHF1 Products)

Synonyms: pcl1 antibody, xpcl1 antibody, MTF2L2 antibody, PCL1 antibody, PHF2 antibody, TDRD19C antibody, hPHF1 antibody, AW557215 antibody, D17Ertd455e antibody, Tctex-3 antibody, Tctex3 antibody, mPcl1 antibody, PHD finger protein 1 L homeolog antibody, PHD finger protein 1 antibody, phf1.L antibody, PHF1 antibody, Phf1 antibody

Background: This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene. Synonyms: Monoclonal PHF1 antibody, Anti-PHF1 antibody, PHD finger protein 1.