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MSH6 antibody
MSH6
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
3A10H7
unconjugated
Product Details anti-MSH6 Antibody
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Target
See all MSH6 Antibodies
MSH6
(MutS Homolog 6 (E. Coli) (MSH6))
Reactivity
All reactivities for MSH6 antibodies
Human
Host
All hosts for MSH6 antibodies
Mouse
Clonality
All clonalities for MSH6 antibodies
Monoclonal
Conjugate
All conjugates for MSH6 antibodies
This MSH6 antibody is un-conjugated
Application
All applications for MSH6 antibodies
Western Blotting (WB), ELISA
Immunogen
MSH6 antibody was raised in Mouse using a purified recombinant fragment of MSH6 expressed in E. coli as the immunogen.
Clone
3A10H7
Isotype
IgG1
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Discover our top product MSH6 Primary Antibody
Alternatives
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Application Details
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Application Notes
ELISA: 1:10,000, WB: 1:500-1:2000 Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
Lot specific
Buffer
Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Target Details for MSH6
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Target
MSH6
(MutS Homolog 6 (E. Coli) (MSH6))
Alternative Name
MSH6 (MSH6 Products )
Synonyms
GTBP antibody, GTMBP antibody, HNPCC5 antibody, HSAP antibody, p160 antibody, cb326 antibody, wu:fb36c12 antibody, LOC100227810 antibody, AU044881 antibody, AW550279 antibody, Gtmbp antibody, mutS homolog 6 antibody, mutS homolog 6 (E. coli) antibody, DNA mismatch repair protein antibody, MSH6 antibody, msh6 antibody, Msh6 antibody
Background
Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair. Synonyms: Monoclonal MSH6 antibody, Anti-MSH6 antibody, Muts Homolog 6 antibody, GTBP antibody, HNPCC5 antibody, HSAP antibody.
Pathways
DNA Damage Repair , Chromatin Binding , Production of Molecular Mediator of Immune Response
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