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CD177 antibody

CD177 Reactivity: Human, Non-Human Primate WB, FACS, IP Host: Mouse Monoclonal MEM-166 unconjugated
Catalog No. ABIN94001
  • Target See all CD177 Antibodies
    CD177 (CD177 Molecule (CD177))
    Reactivity
    • 48
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    Human, Non-Human Primate
    Host
    • 33
    • 20
    Mouse
    Clonality
    • 35
    • 18
    Monoclonal
    Conjugate
    • 27
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD177 antibody is un-conjugated
    Application
    • 30
    • 20
    • 12
    • 10
    • 10
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)
    Specificity
    The antibody MEM-166 reacts with CD177 (Neutrophil specific antigen 1), a 60 kDa GPI-linked cell surface glycoprotein of uPAR family, expressed on granulocytes and in bone marrow early erythroblasts, megakaryocytes, promyelocytes and myelocytes.
    Cross-Reactivity (Details)
    Non-Human Primates, Human
    Purification
    Purified by protein-A affinity chromatography.
    Purity
    > 95 % (by SDS-PAGE)
    Immunogen
    Human granulocytes
    Clone
    MEM-166
    Isotype
    IgG1
    Top Product
    Discover our top product CD177 Primary Antibody
  • Application Notes
    Flow cytometry: Recommended dilution: 1 μg/mL.
    Western blotting: Non-reducing conditions.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Target
    CD177 (CD177 Molecule (CD177))
    Alternative Name
    CD177 (CD177 Products)
    Synonyms
    HNA-2a antibody, HNA2A antibody, NB1 antibody, NB1 GP antibody, PRV-1 antibody, PRV1 antibody, RGD1562941 antibody, CD177 antibody, MGC157159 antibody, 1190003K14Rik antibody, Pdp3 antibody, CD177 molecule antibody, CD177 antigen antibody, CD177 antibody, Cd177 antibody
    Background
    CD177 Molecule,CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).,NB1, PRV1, HNA2A
    Gene ID
    57126
    UniProt
    Q8N6Q3
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