Actin-Like 7A (ACTL7A) (N-Term), (AA 48-75) antibody

Details for Product No. ABIN950263
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Antigen
Synonyms Tact2, Arp7a, T-actin 2
Epitope
N-Term, AA 48-75
(8), (7), (2), (2), (1), (1), (1), (1)
Reactivity
Human
(24), (5), (3)
Host
Rabbit
(23), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(25), (15), (4), (2), (2)
Pubmed 2 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN950263
357.50 $
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Immunogen KLH conjugated synthetic peptide between 48-75 amino acids from the N-terminal region of human ACTL7A
Specificity This antibody reacts to ACTL7A.
Purification Affinity chromatography on Protein A
Alternative Name ACTL7A
Background ACTL7A is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. ACTL7A (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.
Alternate names: Actin-like protein 7A, Actin-like-7-alpha
Gene ID 10881
NCBI Accession NP_006678
Research Area Signaling, Cytoskeleton, Microfilaments
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Humphray, Oliver, Hunt et al.: "DNA sequence and analysis of human chromosome 9." in: Nature, Vol. 429, Issue 6990, pp. 369-74, 2004 (PubMed).

Aberg, Sun, Smelser et al.: "Applying novel genome-wide linkage strategies to search for loci influencing type 2 diabetes and adult height in American Samoa." in: Human biology, Vol. 80, Issue 2, pp. 99-123, 2008 (PubMed).

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