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ARHGEF6 antibody (C-Term)
ARHGEF6
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ARHGEF6 Antibody
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Target
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ARHGEF6
(rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6))
Binding Specificity
All epitopes for ARHGEF6 antibodies
AA 613-641, C-Term
Reactivity
All reactivities for ARHGEF6 antibodies
Human
Host
All hosts for ARHGEF6 antibodies
Rabbit
Clonality
All clonalities for ARHGEF6 antibodies
Polyclonal
Conjugate
All conjugates for ARHGEF6 antibodies
This ARHGEF6 antibody is un-conjugated
Application
All applications for ARHGEF6 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody reacts to ARHGEF6.
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Affinity chromatography on Protein A
Immunogen
KLH conjugated synthetic peptide between 613-641 amino acids from the C-terminal region of human ARHGEF6
Isotype
Ig Fraction
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Discover our top product ARHGEF6 Primary Antibody
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for ARHGEF6
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Target
ARHGEF6
(rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6))
Alternative Name
ARHGEF6 (ARHGEF6 Products )
Synonyms
COOL2 antibody, Cool-2 antibody, MRX46 antibody, PIXA antibody, alpha-PIX antibody, alphaPIX antibody, 1600028C08Rik antibody, 1700038J06Rik antibody, 4930592P22Rik antibody, Rac/Cdc42 guanine nucleotide exchange factor 6 antibody, Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 antibody, ARHGEF6 antibody, Arhgef6 antibody
Background
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation.Synonyms: Alpha-Pix, COOL-2, COOL2, KIAA0006, PAK-interacting exchange factor alpha, PIXA, Rac/Cdc42 guanine nucleotide exchange factor 6, Rho guanine nucleotide exchange factor 6
Gene ID
9459
NCBI Accession
NP_004831
Pathways
Neurotrophin Signaling Pathway
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