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ARHGEF6 Products

(rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6))

Categories

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. [provided by RefSeq, Jul 2008].

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Featured ARHGEF6 Categories

ARHGEF6 Antibodies

High quality antibodies with extensive validation data.

ARHGEF6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ARHGEF6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IP, PLA
Validations
  • (5)
Cat. No. ABIN522926
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB, IHC, IF, ICC
Validations
  • (2)
Cat. No. ABIN6260036
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7167990
Quantity 100 μg
Datasheet Datasheet

Recommended ARHGEF6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345562
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345564
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3089109
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ARHGEF6 products

Kortüm, Harms, Hennighausen, Rosenberger: "αPIX Is a Trafficking Regulator that Balances Recycling and Degradation of the Epidermal Growth Factor Receptor." in: PLoS ONE, Vol. 10, Issue 7, pp. e0132737, (2015) (PubMed).

Synonyms and alternative names related to ARHGEF6

Rac/Cdc42 guanine nucleotide exchange factor 6 (ARHGEF6), Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (Arhgef6), Rac/Cdc42 guanine nucleotide exchange factor 6 (Arhgef6), 1600028C08Rik, 1700038J06Rik, 4930592P22Rik, alpha-PIX, alphaPIX, Cool-2, COOL2, MRX46, PIXA

Protein level used designations for ARHGEF6

  • PAK-interacting exchange factor alpha
  • PAK-interacting exchange factor, alpha
  • Rac/Cdc42 guanine exchange factor (GEF) 6
  • rac/Cdc42 guanine nucleotide exchange factor 6
  • rho guanine nucleotide exchange factor 6
  • alpha PIX Rho GTPase guanine nucleotide exchange factor
  • rac/cdc42 guanine nucleotide exchange factor 6
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