BACH1 antibody (BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1) (C-Term)

Details for Product anti-BACH1 Antibody No. ABIN950595, Supplier: Log in to see
Antigen
  • zgc:112205
  • BACH1
  • 6230421P05Rik
  • AI323795
  • BACH-1
  • BTB and CNC homology 1, basic leucine zipper transcription factor 1
  • BTB and CNC homology 1
  • BACH1
  • bach1
  • Bach1
Epitope
C-Term, AA 669-698
13
9
9
8
7
6
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
100
13
9
5
1
1
Host
Rabbit
70
17
14
1
Clonality
Polyclonal
Conjugate
This BACH1 antibody is un-conjugated
4
3
3
3
3
3
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
94
49
16
16
15
7
3
3
2
2
2
1
Options
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Immunogen KLH conjugated synthetic peptide between 669-698 amino acids from the C-terminal region of human BACH1
Isotype Ig
Specificity This antibody reacts to BACH1.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name BACH1 (BACH1 Antibody Abstract)
Background This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene.Synonyms: BTB and CNC homolog 1, HA2303, Transcription regulator protein BACH1, basic leucine zipper transcription factor 1
Gene ID 571
NCBI Accession NP_001177
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-BACH1 antibody (BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1) (C-Term) (ABIN950595) BACH1 Antibody (C-term) western blot analysis in ZR-75-1 cell line lysates (35µg/lane...
Background publications Miyazaki, Kirino, Takeno, Samukawa, Hama, Tanaka, Yamaji, Ueda, Tomita, Fujita, Ishigatsubo: "Expression of heme oxygenase-1 in human leukemic cells and its regulation by transcriptional repressor Bach1." in: Cancer science, Vol. 101, Issue 6, pp. 1409-16, 2010 (PubMed).

Hou, Tian, Zheng, Bonkovsky: "MicroRNA-196 represses Bach1 protein and hepatitis C virus gene expression in human hepatoma cells expressing hepatitis C viral proteins." in: Hepatology (Baltimore, Md.), Vol. 51, Issue 5, pp. 1494-504, 2010 (PubMed).

Gong, Kim, Leung, Glover, Chen: "BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control." in: Molecular cell, Vol. 37, Issue 3, pp. 438-46, 2010 (PubMed).