C5AR1 antibody (Complement Component 5a Receptor 1) (AA 178-205)

Details for Product anti-C5AR1 Antibody No. ABIN951423, Supplier: Log in to see
Antigen
  • C5AR1
  • C5R1
  • GPR77
  • C5aR
  • C5r1
  • Cd88
  • D7Msu1
  • C5A
  • C5AR
  • CD88
  • complement component 5a receptor 1
  • C5a anaphylatoxin chemotactic receptor-like
  • C5AR1
  • c5ar1
  • LOC100352978
  • C5ar1
Epitope
AA 178-205, Middle Region
27
20
15
14
13
9
8
6
6
5
5
5
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
185
83
28
20
16
11
4
4
2
2
1
1
1
1
1
1
1
1
Host
Rabbit
111
85
76
1
Clonality
Polyclonal
Conjugate
This C5AR1 antibody is un-conjugated
31
13
11
9
6
6
4
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
188
100
53
47
41
29
24
13
11
11
5
4
3
2
2
2
2
2
1
1
Options
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Immunogen KLH conjugated synthetic peptide between 178-205 amino acids from the Central region of human C5AR1
Isotype Ig
Specificity This antibody reacts to CD88.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name CD88 / C5R1 (C5AR1 Antibody Abstract)
Background Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.Synonyms: C5AR1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, Complement Component 5a Receptor 1
Gene ID 728
NCBI Accession NP_001727
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-C5AR1 antibody (Complement Component 5a Receptor 1) (AA 178-205) (ABIN951423) C5AR1 Antibody (Center) flow cytometric analysis of A549 cells (right histogram) comp...
Western Blotting (WB) image for anti-C5AR1 antibody (Complement Component 5a Receptor 1) (AA 178-205) (ABIN951423) C5AR1 Antibody (Center) western blot analysis in A549 cell line lysates (35µg/lane).T...
Background publications Skeie, Fingert, Russell, Stone, Mullins: "Complement component C5a activates ICAM-1 expression on human choroidal endothelial cells." in: Investigative ophthalmology & visual science, Vol. 51, Issue 10, pp. 5336-42, 2010 (PubMed).

Nishiura, Tokita, Li, Harada, Woodruff, Taylor, Nsiama, Nishino, Yamamoto: "The role of the ribosomal protein S19 C-terminus in Gi protein-dependent alternative activation of p38 MAP kinase via the C5a receptor in HMC-1 cells." in: Apoptosis : an international journal on programmed cell death, Vol. 15, Issue 8, pp. 966-81, 2010 (PubMed).

Marc, Kristan, Rozman, Kern, Flezar, Kosnik, Korosec: "Complement factor C5a in acute exacerbation of Chronic Obstructive Pulmonary Disease." in: Scandinavian journal of immunology, Vol. 71, Issue 5, pp. 386-91, 2010 (PubMed).

Han, Lan, Park, Lee, Park, Ahn, Shin, Kang, Koo, Seo, Choi, Ahn, Chanock, Kim, Rothman, Kang: "Polymorphisms in innate immunity genes and risk of childhood leukemia." in: Human immunology, Vol. 71, Issue 7, pp. 727-30, 2010 (PubMed).

Rajaraman, Brenner, Neta, Pfeiffer, Wang, Yeager, Thomas, Fine, Linet, Rothman, Chanock, Inskip: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).