CPSF3L antibody (N-Term)

Catalog No. ABIN951683

Product Details anti-CPSF3L Antibody

Target: CPSF3L (Cleavage and Polyadenylation Specific Factor 3-Like (CPSF3L))

Binding Specificity: AA 98-126, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPSF3L antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human CPSF3L (N-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 98-126 amino acids from the N-terminal region of Human CPSF3L Genename: CPSF3L

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CPSF3L

Target: CPSF3L (Cleavage and Polyadenylation Specific Factor 3-Like (CPSF3L))

Alternative Name: CPSF3L (CPSF3L Products)

Synonyms: DDBDRAFT_0204486 antibody, DDBDRAFT_0234100 antibody, DDB_0204486 antibody, DDB_0234100 antibody, int11 antibody, CPSF73L antibody, INT11 antibody, INTS11 antibody, RC-68 antibody, RC68 antibody, 2410006F12Rik antibody, AU044035 antibody, RGD1306841 antibody, zgc:110671 antibody, CPSF3L antibody, DKFZp469C1432 antibody, cleavage and polyadenylation specific factor 3-like antibody, integrator complex subunit 11 antibody, RNA-metabolising metallo-beta-lactamase domain-containing protein antibody, microRNA 6727 antibody, CPSF3L antibody, INTS11 antibody, ints11 antibody, Ints11 antibody, MIR6727 antibody

Background: The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A, MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1, MIM 180680) and U2 (RNU2, MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).Synonyms: CPSF3-like protein, Cleavage and polyadenylation-specific factor 3-like protein, INTS11, Int11, Integrator complex subunit 11, Protein related to CPSF subunits of 68 kDa, RC-68, RC68

Molecular Weight: 67663 Da

Gene ID: 54973

NCBI Accession: NP_060341