CPSF3L antibody (AA 151-250) (Biotin)

Catalog No. ABIN2808205

The Rabbit Polyclonal anti-CPSF3L antibody is suitable to detect CPSF3L in samples from Human. It has been validated for WB, IHC (p) and IHC (fro).

Quick Overview for CPSF3L antibody (AA 151-250) (Biotin) (ABIN2808205)

Target: CPSF3L (Cleavage and Polyadenylation Specific Factor 3-Like (CPSF3L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPSF3L antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CPSF3L Antibody (Biotin)

Binding Specificity: AA 151-250

Purpose: INT11/CPSF3L Polyclonal Antibody, Biotin Conjugated

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Horse,Zebrafish,Orangutan,Rhesus monkey,Gorilla,Opossum,Elephant

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human INT11

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CPSF3L

Target: CPSF3L (Cleavage and Polyadenylation Specific Factor 3-Like (CPSF3L))

Alternative Name: INT11

Background:

Synonyms: RC68, INT11, RC-68, INTS11, CPSF73L, Integrator complex subunit 11, Cleavage and polyadenylation-specific factor 3-like protein, CPSF3-like protein, Protein related to CPSF subunits of 68 kDa, CPSF3L

Background: Catalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage.

Gene ID: 54973

UniProt: Q5TA45