Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH) (N-Term), (AA 34-64) antibody

Details for Product No. ABIN951969
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Antigen
Synonyms CG1543, DBH, Dbh, Dmel\\CG1543, T beta h, TBH, TBetaH, TBetah, TBh, TbetaH, TbetaM, Tbetah, tbh, DBM, DOPBHY, Tbh
Epitope
N-Term, AA 34-64
(16), (13), (10), (7), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(76), (26), (25), (17), (4), (2), (2), (1), (1), (1), (1), (1)
Host
Rabbit
(60), (20), (12), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF), ELISA, Western Blotting (WB)
(77), (29), (24), (18), (14), (10), (9), (7), (3), (2), (1), (1), (1)
Pubmed 4 references available
Quantity 0.4 mL
Shipping to United States (Change)
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Catalog No. ABIN951969
357.50 $
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Immunogen KLH conjugated synthetic peptide between 34-64 amino acids from the N-terminal region of Human DBH.
Specificity This antibody recognizes Human DBH (N-term).
Purification Affinity Chromatography on Protein A
Alternative Name Dopamine beta-hydroxylase
Background The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. [provided by RefSeq].
Alternate names: DBH, DBM, DOPO, Dopamine beta-monooxygenase
Molecular Weight 69065 Da
Gene ID 1621
NCBI Accession NP_000778
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Punia, Das, Behari et al.: "Role of polymorphisms in dopamine synthesis and metabolism genes and association of DBH haplotypes with Parkinson's disease among North Indians." in: Pharmacogenetics and genomics, Vol. 20, Issue 7, pp. 435-41, 2010 (PubMed).

Fernàndez-Castillo, Ribasés, Roncero et al.: "Association study between the DAT1, DBH and DRD2 genes and cocaine dependence in a Spanish sample." in: Psychiatric genetics, Vol. 20, Issue 6, pp. 317-20, 2010 (PubMed).

Ruaño, Thompson, Kane et al.: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" in: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

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