DPH1 antibody (C-Term)
Quick Overview for DPH1 antibody (C-Term) (ABIN951975)
Target
See all DPH1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 383-412, C-Term
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Specificity
- This antibody recognizes Human DPH1 / OVAC1 (C-term).
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Purification
- Affinity Chromatography on Protein A
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Immunogen
- KLH conjugated synthetic peptide between 383-412 amino acids from the C-terminal region of Human DPH1
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DPH1 (DPH1 Homolog (DPH1))
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Background
- Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM].Synonyms: DPH1 homolog, DPH2L, DPH2L1, Diphthamide biosynthesis protein 1, Diphthamide biosynthesis protein 2 homolog-like 1, Ovarian cancer-associated gene 1 protein
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Molecular Weight
- 48805 Da
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Gene ID
- 1801
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NCBI Accession
- NP_001374
Target
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