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DPH1 antibody (C-Term)

This anti-DPH1 antibody is a Rabbit Polyclonal antibody detecting DPH1 in WB and EIA. Suitable for Human.
Catalog No. ABIN951975

Quick Overview for DPH1 antibody (C-Term) (ABIN951975)

Target

See all DPH1 Antibodies
DPH1 (DPH1 Homolog (DPH1))

Reactivity

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  • 2
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  • 1
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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This DPH1 antibody is un-conjugated

Application

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Binding Specificity

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    AA 383-412, C-Term

    Specificity

    This antibody recognizes Human DPH1 / OVAC1 (C-term).

    Purification

    Affinity Chromatography on Protein A

    Immunogen

    KLH conjugated synthetic peptide between 383-412 amino acids from the C-terminal region of Human DPH1

    Isotype

    Ig Fraction
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) Sodium Azide as preservative

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    DPH1 (DPH1 Homolog (DPH1))

    Background

    Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM].Synonyms: DPH1 homolog, DPH2L, DPH2L1, Diphthamide biosynthesis protein 1, Diphthamide biosynthesis protein 2 homolog-like 1, Ovarian cancer-associated gene 1 protein

    Molecular Weight

    48805 Da

    Gene ID

    1801

    NCBI Accession

    NP_001374
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