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EGF antibody (Middle Region)
EGF
Reactivity: Human, Mouse
WB, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-EGF Antibody
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Target
See all EGF Antibodies
EGF
(Epidermal Growth Factor (EGF))
Binding Specificity
All epitopes for EGF antibodies
AA 689-720, Middle Region
Reactivity
All reactivities for EGF antibodies
Human, Mouse
Host
All hosts for EGF antibodies
Rabbit
Clonality
All clonalities for EGF antibodies
Polyclonal
Conjugate
All conjugates for EGF antibodies
This EGF antibody is un-conjugated
Application
All applications for EGF antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody reacts to EGF.
Cross-Reactivity (Details)
Species reactivity (tested):Human and Mouse.
Purification
Affinity chromatography on Protein A
Immunogen
KLH conjugated synthetic peptide between 689-720 amino acids from the Central region of human EGF
Isotype
Ig Fraction
Top Product
Discover our top product EGF Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS, 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for EGF
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Target
EGF
(Epidermal Growth Factor (EGF))
Alternative Name
EGF (EGF Products )
Synonyms
HOMG4 antibody, URG antibody, AI790464 antibody, CEGF antibody, epidermal growth factor antibody, pro-epidermal growth factor antibody, EGF antibody, egf antibody, CpipJ_CPIJ020278 antibody, Egf antibody
Background
This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.Synonyms: Epidermal growth factor, HOMG4, Pro-epidermal growth factor, URG, Urogastrone
Molecular Weight
133994 Da
Gene ID
1950
NCBI Accession
NP_001954
Pathways
NF-kappaB Signaling , RTK Signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Regulation of Carbohydrate Metabolic Process , Hepatitis C , Protein targeting to Nucleus , Interaction of EGFR with phospholipase C-gamma , Thromboxane A2 Receptor Signaling , EGFR Downregulation
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