FOXA1 antibody (Forkhead Box A1) (AA 270-299)

Details for Product anti-FOXA1 Antibody No. ABIN952360, Supplier: Log in to see
Antigen
  • FoxA4a
  • XFD-1
  • fkh1
  • foxa1
  • pintallavis
  • xfkh1
  • xkfh-1
  • HNF3-alpha
  • HNF3alpha
  • Hnf3a
  • fkh2
  • tFoxA1
  • tcf3a
  • xfkh2
  • fkh
  • FOXA1
  • Ci-fkh
  • foxa3
  • Foxa1
  • fkd7
  • forkhead-7
  • hnf3a
  • HNF3A
  • TCF3A
  • HNF-3a
  • Hnf-3a
  • Tcf-3a
  • Tcf3a
  • forkhead box A4
  • forkhead box A1
  • forkhead homolog
  • Me-FKH1
  • foxa4
  • foxa1
  • fkh
  • FOXA1
  • foxa3
  • LOC100301627
  • foxa1-b
  • Foxa1
Alternatives
anti-Human FOXA1 antibody for ChIP DNA-Sequencing
Epitope
AA 270-299, Middle Region
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Reactivity
Human
349
110
46
12
9
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3
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2
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Host
Rabbit
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84
20
Clonality
Polyclonal
Conjugate
This FOXA1 antibody is un-conjugated
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Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
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80
13
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7
7
2
1
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Options
Supplier
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Immunogen KLH conjugated synthetic peptide between 270-299 amino acids from the Central region of Human FOXA1 / TCF3A
Isotype Ig
Specificity This antibody recognizes Human FOXA1 / TCF3A (Center).
Purification Protein A column, followed by peptide affinity purification
Alternative Name FOXA1 / TCF3A (FOXA1 Antibody Abstract)
Background This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.Synonyms: Forkhead box protein A1, HNF-3-alpha, HNF-3A, HNF3A, Hepatocyte nuclear factor 3-alpha, TCF-3A, Transcription factor 3A
Molecular Weight 49148 Da
Gene ID 3169
NCBI Accession NP_004487
Pathways Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-FOXA1 antibody (Forkhead Box A1) (AA 270-299) (ABIN952360) Western blot analysis of FOXA1 / TCF3A Antibody (Center) in 293 cell line lysates (35...
Background publications Hu, Gardner-Stephen, Severi, Gregory, Treloar, Giles, English, Hopper, Tilley, Mackenzie: "A novel polymorphism in a forkhead box A1 (FOXA1) binding site of the human UDP glucuronosyltransferase 2B17 gene modulates promoter activity and is associated with altered levels of circulating androstane-3α,17β-diol glucuronide." in: Molecular pharmacology, Vol. 78, Issue 4, pp. 714-22, 2010 (PubMed).

Zhang, Liang, Li, Xuan, Wang, Wang, Shi, Zhang, Shang: "CCCTC-binding factor acts upstream of FOXA1 and demarcates the genomic response to estrogen." in: The Journal of biological chemistry, Vol. 285, Issue 37, pp. 28604-13, 2010 (PubMed).

Bernardo, Lozada, Miedler, Harburg, Hewitt, Mosley, Godwin, Korach, Visvader, Kaestner, Abdul-Karim, Montano, Keri: "FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis." in: Development (Cambridge, England), Vol. 137, Issue 12, pp. 2045-54, 2010 (PubMed).

Liu, Niu, Wang, Yu, Zhang, Liu: "[Diagnostic and prognostic significance of FOXA1 expression in molecular subtypes of breast invasive ductal carcinomas]." in: Zhonghua yi xue za zhi, Vol. 90, Issue 20, pp. 1403-7, 2010 (PubMed).

Song, Washington, Crawford: "Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer." in: Cancer research, Vol. 70, Issue 5, pp. 2115-25, 2010 (PubMed).