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Homeodomain Interacting Protein Kinase 1 (HIPK1) (AA 892-922), (C-Term) antibody

Details for Product No. ABIN952740, Supplier: Login to see
Antigen
  • HIPK1
  • myak
  • nbak2
  • hipk1
  • Myak
  • Nbak2
  • 1110062K04Rik
Epitope
AA 892-922, C-Term
17
15
15
10
6
2
2
1
1
1
1
Reactivity
Human
54
5
3
1
1
Host
Rabbit
30
26
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
41
31
22
9
8
2
1
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Immunogen KLH conjugated synthetic peptide between 892-922 amino acids from the C-terminal region of human HIPK1
Isotype Ig
Specificity This antibody recognizes Human HIPK1 (C-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name HIPK1 (HIPK1 Antibody Abstract)
Background The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. Alternative splicing results in four transcript variants encoding four distinct isoforms.Synonyms: Homeodomain-interacting protein kinase 1, KIAA0630
Molecular Weight 130843 Da
Gene ID 204851
NCBI Accession NP_689909
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Homeodomain Interacting Protein Kinase 1 (HIPK1) (AA 892-922), (C-Term) antibody (ABIN952740) Immunohistochemistry analysis in formalin fixed and paraffin embedded human breast ca...
Western Blotting (WB) image for anti-Homeodomain Interacting Protein Kinase 1 (HIPK1) (AA 892-922), (C-Term) antibody (ABIN952740) Western blot analysis of HIPK1 Antibody (C-term) Cat.-No AP52049PU-N pre-incubated wi...
Background publications Matre, Nordgård, Alm-Kristiansen et al.: "HIPK1 interacts with c-Myb and modulates its activity through phosphorylation." in: Biochemical and biophysical research communications, Vol. 388, Issue 1, pp. 150-4, 2009 (PubMed).

Li, Zhang, Luo et al.: "Tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal-regulating kinase 1-JNK/p38 activation." in: The Journal of biological chemistry, Vol. 280, Issue 15, pp. 15061-70, 2005 (PubMed).

Rush, Moritz, Lee et al.: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, 2005 (PubMed).

Colland, Jacq, Trouplin et al.: "Functional proteomics mapping of a human signaling pathway." in: Genome research, Vol. 14, Issue 7, pp. 1324-32, 2004 (PubMed).

Song, Lee: "Role of the ASK1-SEK1-JNK1-HIPK1 signal in Daxx trafficking and ASK1 oligomerization." in: The Journal of biological chemistry, Vol. 278, Issue 47, pp. 47245-52, 2003 (PubMed).