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IRAK4 antibody (N-Term)
IRAK4
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IRAK4 Antibody
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Target
See all IRAK4 Antibodies
IRAK4
(Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
Binding Specificity
All epitopes for IRAK4 antibodies
AA 32-60, N-Term
Reactivity
All reactivities for IRAK4 antibodies
Human
Host
All hosts for IRAK4 antibodies
Rabbit
Clonality
All clonalities for IRAK4 antibodies
Polyclonal
Conjugate
All conjugates for IRAK4 antibodies
This IRAK4 antibody is un-conjugated
Application
All applications for IRAK4 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human IRAK4 (N-term).
Purification
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 32-60 amino acids from the N-terminal region of Human IRAK4.
Isotype
Ig Fraction
Top Product
Discover our top product IRAK4 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for IRAK4
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Target
IRAK4
(Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
Alternative Name
IRAK4 (IRAK4 Products )
Synonyms
zgc:55553 antibody, IRAK4 antibody, ipd1 antibody, irak-4 antibody, ny-ran-64 antibody, ny-ren-64 antibody, ren64 antibody, irak4 antibody, IPD1 antibody, IRAK-4 antibody, NY-REN-64 antibody, REN64 antibody, 8430405M07Rik antibody, 9330209D03Rik antibody, interleukin 1 receptor associated kinase 4 antibody, interleukin-1 receptor-associated kinase 4 antibody, IRAK4 antibody, irak4 antibody, Irak4 antibody
Background
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: IRAK-4, Interleukin-1 receptor-associated kinase-like, NY-REN-64
Molecular Weight
51530 Da
Gene ID
51135
NCBI Accession
NP_001107654
Pathways
NF-kappaB Signaling , TLR Signaling , Activation of Innate immune Response , Toll-Like Receptors Cascades
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