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Chemokine (C-C Motif) Ligand 7 (CCL7) (AA 24-54), (Middle Region) antibody

Details for Product No. ABIN953357, Supplier: Log in to see
Antigen
  • CCL7
  • FIC
  • MARC
  • MCP-3
  • MCP3
  • NC28
  • SCYA6
  • SCYA7
  • Scya7
  • fic
  • marc
  • mcp3
Epitope
AA 24-54, Middle Region
13
10
9
7
6
5
4
4
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
174
26
6
2
Host
Rabbit
99
70
28
2
1
Clonality
Polyclonal
Conjugate
Un-conjugated
27
14
13
8
6
6
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
145
131
30
19
13
13
9
8
6
6
3
3
3
3
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 24-54 amino acids from the Central region of human CCL7
Isotype Ig
Specificity This antibody reacts to CCL7.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name MCP3 / CCL7 (CCL7 Antibody Abstract)
Background This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q.Synonyms: C-C motif chemokine 7, CCL-7, MCP-3, Macrophage Chemotactic Protein-3, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, NC28, SCYA6, SCYA7, Small-inducible cytokine A7
Molecular Weight 11200 Da
Gene ID 6354
NCBI Accession NP_006264
Research Area Cytokines, Chemokines
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Chemokine (C-C Motif) Ligand 7 (CCL7) (AA 24-54), (Middle Region) antibody (ABIN953357) CCL7 Antibody (Center) western blot analysis in K562 cell line lysates (35µg/la...
Background publications McGovern, Jones, Taylor et al.: "Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease." in: Human molecular genetics, Vol. 19, Issue 17, pp. 3468-76, 2010 (PubMed).

Schuurhof, Bont, Siezen et al.: "Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls." in: Pediatric pulmonology, Vol. 45, Issue 6, pp. 608-13, 2010 (PubMed).

Han, Lan, Park et al.: "Polymorphisms in innate immunity genes and risk of childhood leukemia." in: Human immunology, Vol. 71, Issue 7, pp. 727-30, 2010 (PubMed).

Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).