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NUDT15 antibody (C-Term)
NUDT15
Reactivity: Human, Mouse
WB, FACS, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NUDT15 Antibody
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Target
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NUDT15
(Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
Binding Specificity
All epitopes for NUDT15 antibodies
AA 89-118, C-Term
Reactivity
All reactivities for NUDT15 antibodies
Human, Mouse
Host
All hosts for NUDT15 antibodies
Rabbit
Clonality
All clonalities for NUDT15 antibodies
Polyclonal
Conjugate
All conjugates for NUDT15 antibodies
This NUDT15 antibody is un-conjugated
Application
All applications for NUDT15 antibodies
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes NUDT15.
Cross-Reactivity (Details)
Species reactivity (tested):Human, Mouse
Purification
Purified through a Protein A column followed by peptide affinity purification
Immunogen
Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 89-118aa) of human NUDT15.
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for NUDT15
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Target
NUDT15
(Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
Alternative Name
NUDT15 (NUDT15 Products )
Synonyms
MTH2 antibody, RP11-90M2.1 antibody, 6530403O17 antibody, A730068G11Rik antibody, nudix hydrolase 15 antibody, nudix (nucleoside diphosphate linked moiety X)-type motif 15 antibody, NUDT15 antibody, Nudt15 antibody
Background
Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear (By similarity). May have a role in DNA synthesis and cell cycle progression throught the interaction with PCNA.Synonyms: 7, 8-dihydro-8-oxoguanine-triphosphatase NUDT15, MTH2, MutT homolog 2, Nucleoside diphosphate-linked moiety X motif 15, Nudix motif 15, Probable 8-oxo-dGTP diphosphatase NUDT15
Gene ID
55270
NCBI Accession
NP_060753
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