zgc:77476 antibody, wu:fc06g09 antibody, PNPLA9 antibody, MGC83523 antibody, PLA2G6 antibody, BB112799 antibody, iPLA(2)beta antibody, iPLA2 antibody, iPLA2beta antibody, CaI-PLA2 antibody, GVI antibody, INAD1 antibody, IPLA2-VIA antibody, NBIA2 antibody, NBIA2A antibody, NBIA2B antibody, PARK14 antibody, PLA2 antibody, iPla2 antibody, phospholipase A2, group VI (cytosolic, calcium-independent) antibody, phospholipase A2 group VI antibody, phospholipase A2 group VI S homeolog antibody, 85/88 kDa calcium-independent phospholipase A2 antibody, phospholipase A2, group VI antibody, pla2g6 antibody, PLA2G6 antibody, pla2g6.S antibody, LOC100445065 antibody, Pla2g6 antibody
Background
The protein encoded by the PLA2G6 gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells.Synonyms: 85 kDa calcium-independent phospholipase A2, Cal-PLA2, GVI PLA2, Group VI phospholipase A2, IPLA2, PARK14