PTPN14 antibody (C-Term)

Catalog No. ABIN954373

Product Details anti-PTPN14 Antibody

Target: PTPN14 (Protein tyrosine Phosphatase, Non-Receptor Type 14 (PTPN14))

Binding Specificity: AA 861-890, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN14 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes PTPN14 / PEZ at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 861-890aa) of human PTPN14 / PEZ (C-term)

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PTPN14

Target: PTPN14 (Protein tyrosine Phosphatase, Non-Receptor Type 14 (PTPN14))

Alternative Name: PTPN14 / PEZ (PTPN14 Products)

Synonyms: PEZ antibody, PTP36 antibody, C130080N23Rik antibody, OTTMUSG00000022087 antibody, protein tyrosine phosphatase, non-receptor type 14 antibody, PTPN14 antibody, Ptpn14 antibody

Background: The protein encoded by the PTPN14 gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia.Synonyms: PTP36, PTPD2, Protein-tyrosine phosphatase pez, Tyrosine-protein phosphatase non-receptor type 14

Gene ID: 5784

NCBI Accession: NP_005392