HTR7 antibody (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled)) (C-Term)

Details for Product anti-HTR7 Antibody No. ABIN954739, Supplier: Log in to see
Antigen
  • 5-HT7
  • 5-HT-dro
  • 5-HT-dro1
  • 5-HT7Dro
  • 5-HT[7]Dro
  • 5-HT[[7Dro]]
  • 5-HT[[7]]
  • 5-HT[[7]]Dro
  • 5-HT[[dro1]]
  • 5-HTdro1
  • 5HT-7
  • 5HT-R1
  • 5HT-dro
  • 5HT-dro1
  • 5HT[[7Dro]]
  • 5htdror
  • CG12073
  • DRO1
  • Dm5HTdro1
  • Dmel\\CG12073
  • 5Ht7
  • 5HT7
  • htr7-A
  • 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
  • Serotonin receptor 7
  • 5-hydroxytryptamine (serotonin) receptor 7
  • HTR7
  • 5-HT7
  • Htr7
  • htr7
Alternatives
anti-Human HTR7 antibody for ELISA
Epitope
C-Term, AA 404-433
49
18
14
4
3
3
3
2
2
1
1
1
1
1
Reactivity
Human
114
22
20
18
9
9
7
4
3
3
3
2
2
2
2
1
1
1
Host
Rabbit
101
15
Clonality
Polyclonal
Conjugate
This HTR7 antibody is un-conjugated
3
3
3
3
3
3
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
52
45
43
19
12
4
1
1
1
Options
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Immunogen KLH conjugated synthetic peptide between 404-433 amino acids from the C-terminal region of Human Serotonin receptor 7 (HTR7).
Isotype Ig
Specificity This antibody recognizes Human Serotonin receptor 7 (HTR7) (C-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name Serotonin Receptor 7 (HTR7) (HTR7 Antibody Abstract)
Background The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends.Synonyms: 5-HT-7, 5-hydroxytryptamine receptor 7, 5HT7
Molecular Weight 53555 Da
Gene ID 3363
NCBI Accession NP_000863
Pathways JAK-STAT Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-HTR7 antibody (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled)) (C-Term) (ABIN954739) Western blot analysis of HTR7 Antibody (C-term) in MDA-MB231 cell line lysates (35ug/...
Background publications Ruaño, Thompson, Kane, Pullinger, Windemuth, Seip, Kocherla, Holford, Wu: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" in: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, 2010 (PubMed).

Pinheiro, Bulik, Thornton, Sullivan, Root, Bloss, Berrettini, Schork, Kaye, Bergen, Magistretti, Brandt, Crawford, Crow, Fichter, Goldman, Halmi, Johnson, Kaplan, Keel, Klump, La Via, Mitchell, Strober, Rotondo, Treasure, Woodside: "Association study of 182 candidate genes in anorexia nervosa." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 5, pp. 1070-80, 2010 (PubMed).

Corominas, Sobrido, Ribasés, Cuenca-León, Blanco-Arias, Narberhaus, Roig, Leira, López-González, Macaya, Cormand: "Association study of the serotoninergic system in migraine in the Spanish population." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 1, pp. 177-84, 2009 (PubMed).

Wei, Wang, Xuan, Che, Du, Qin, Xing, Gu, Yang, Li, Li, Feng, He, Xing: "Association analysis of serotonin receptor 7 gene (HTR7) and risperidone response in Chinese schizophrenia patients." in: Progress in neuro-psychopharmacology & biological psychiatry, Vol. 33, Issue 3, pp. 547-51, 2009 (PubMed).

Iceta, Mesonero, Aramayona, Alcalde: "Expression of 5-HT1A and 5-HT7 receptors in Caco-2 cells and their role in the regulation of serotonin transporter activity." in: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, Vol. 60, Issue 1, pp. 157-64, 2009 (PubMed).